CARDIOVASCULAR DISEASE RISK SCORE PREDICTION MODELS FOR WOMEN AND ITS APPLICABILITY TO ASIANS





Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies

Oral delivery of macromolecules requires permeation enhancers (PEs) adaptable to formulation.Sucrose laurate (SL) (D1216), a food grade surfactant, was assessed in Caco-2 monolayers, isolated rat intestinal tissue mucosae, and rat intestinal instillations.Accordingly, 1 mM SL increased Coaxial Tools the apparent permeability coefficient (Papp) of [

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